• While resistance to imatinib is rare in patients treated

  2019-06-27

  

  While resistance to imatinib is rare in patients treated in CML-CP, resistance does eventually develop in the majority of patients treated in the advanced phases. In a high proportion of patients who develop secondary resistance after initial responses, point mutations in the BCR-ABL kinase domain h

• Si se orienta seg n

  2019-06-26

  

  Si se orienta según el procedimiento de la fórmula de transición adoptada, el mejor tipo de justicia transicional para Colombia sería el de las transiciones democráticamente legitimadas, el cual consiste en: Un modelo óptimo sería entonces el que combine tanto los perdones “responsabilizantes” y el

• Introduction Acute erythroleukemia AEL is a rare subtype of

  2019-06-26

  

  Introduction Acute erythroleukemia (AEL) is a rare subtype of acute myeloid leukemia (AML), accounting for 3–5% of all AML cases. It is characterized by the expansion of erythroblasts in the bone marrow (BM). Its clinical presentation often resembles myelodysplastic syndromes (MDS), both in terms o

• The development in high income countries shows the

  2019-06-26

  

  The development in high-income countries shows the possibilities for progress in twin health and survival: Danish twins born between 1870 and 1900 had higher early-life mortality rates than twins born in the late 20th century and contemporary sub-Saharan twins, with about 40% under-6 mortality (doub

• SQTS is relatively rare but should be

  2019-06-26

  

  SQTS is relatively rare, but should be considered if the QT interval is markedly abbreviated and the ST segment is nearly absent with peaked and symmetrical T waves. Thus far, mutations in 5 different genes have been found, but genetic testing remains investigational because these genes account for

• Next we evaluated the interatrial

  2019-06-26

  

  Next, we evaluated the interatrial and interatrioventricular synchrony because a long contraction time between the right and left atria was observed during the SSA procedure, dissection of the atrial septum, and patch closure. We were primarily concerned with determining whether the timing of the le

• br Methods br Results The clinical genetic electrocardiograp

  2019-06-26

  

  Methods Results The clinical, genetic, electrocardiographic, and electrophysiological characteristics of the study patients are shown in Table 1. Eight of the 45 patients were symptomatic, having a history of syncope (n=3) or aborted SCD (n=5). The remaining 37 patients were asymptomatic, alth

• Introduction Lung cancer is the most common and deadly malig

  2019-06-26

  

  Introduction Lung cancer is the most common and deadly malignancy in Taiwan, the cause of an estimated 33,919 new cases between 2002 and 2008. Although the 5-year survival rate is only 15.9%, the overall survival rate is as high as 60.7% in patients whose tumors are confined to the primary site at

• br Adverse events Treatment reported toxicities were

  2019-06-26

  

  Adverse events Treatment reported toxicities were similar to those previously reported [23]. Discussion Several other studies have addressed the same issue using different bisphosphonates. The SABRE study randomised breast cancer patients taking anastrozole with a T-score of between −1 and −2

• br Discussion The rate of ERP in young

  2019-06-26

  

  Discussion The rate of ERP in young, healthy men in northeastern Thailand was 10.3%. This is higher than the rate reported in the US (3.3–6.1%) [12]. In the US report, the mean age of the study population was 45 years, which was older than the age of subjects in our study. Another report from the

• Pranlukast weight La expansi n exportadora de

  2019-06-26

  

  La expansión exportadora de Argentina hacia Colombia, Perú y Venezuela respondió Pranlukast weight distintas razones, pero los mercados obviamente tuvieron mucho que ver. No fue casual que Colombia, por ejemplo, concentrara más de 65% de sus importaciones de Argentina en bienes primarios, pues la a

• The presence or absence of atrial potentials could

  2019-06-25

  

  The presence or absence of atrial potentials could not be confirmed by the VEGM. Consequently, atrial potentials with atrial event markers could not be differentiated from FFRW or noise activity in the VEGM (Fig. 6). In addition, tiny suspected atrial potentials without any atrial event markers coul

• Our results are consistent with previous findings in

  2019-06-25

  

  Our results are consistent with previous findings in other malignancies. Functional assays revealed that ectopic expression of UCA1 promoted cell proliferation and/or reduced cell apoptosis in non-small cell lung cancer [19], breast cancer [18], colorectal cancer [28], and renal cell carcinoma [23].

• Caspase Inhibitor Set I br Vascular cells and the peribiliar

  2019-06-25

  

  Vascular cells and the peribiliary vascular plexus The liver is a highly vascularized organ that receives dual blood supplies from the hepatic portal vein (HPV) and hepatic Caspase Inhibitor Set I (Fig. 1). The HPV delivers approximately 75% of the total blood supply that the liver receives and c

• br It s that time of year again when

  2019-06-25

  

  It\'s that time of year again when we ask readers to submit photographs for our annual Highlights photography competition. We are looking for striking images that arrest our attention about any topic in medicine, from global health to clinical medicine, from the individual person to populations. A

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