• While it has been reported that

  2019-05-17

  

  While it has been reported that the combination therapy of As2O3 and ATRA is highly effective not only as the front-line treatment [6], but also in relapsed and treatment-refractory APL patients [7], showing fewer adverse events than the combination of ATRA and chemotherapeutic drugs, the efficacy a

• rifampicin Myeloid sarcoma can be observed as a

  2019-05-17

  

  Myeloid sarcoma can be observed as a de novo malignancy (without leukemic presentation in peripheral blood and bone marrow), during the course of acute myeloid leukemia (AML), affecting 2.5–9% of all AML patients, myelodysplastic syndromes (MDS) or myeloproliferative neoplasms (MPNs, both chronic my

• But in comes the good news from these three

  2019-05-17

  

  But in comes the good news from these three NEOVITA studies: there are other effective, feasible interventions that can be implemented everywhere. Rajiv Bahl and colleagues identify that early initiation of breastfeeding and exclusive breastfeeding have independent beneficial effects on neonatal mo

• Could new approaches to global nutrition lead to interventio

  2019-05-17

  

  Could new approaches to global nutrition lead to interventions that would make children grow tall without putting on excessive fat, as is the case for present-day piglets? Animal science has been addressing this issue for a long time, although with rigorous studies that cannot be conducted in humans

• Numbers studies also showed that the MSCs

  2019-05-17

  

  Numbers studies also showed that the MSCs have the capacity to differentiate into multiple mesenchymal tissues both in vitro and in vivo, including osteoblast [25,34], condrocyte [35,36], adipocyte [37,38], tendon [39,40], skeletal muscle cells [39], cardiomyocyte [41,42] and hematopoietic supportin

• p450 inhibitors In the normal BMD subgroup there was progres

  2019-05-17

  

  In the normal BMD subgroup, there was progressive bone loss over 3 years at the spine and hip (5.4% and 4.5%, respectively). This finding is consistent with the ATAC data [5]. Two patients required alendronate triggered by clinical events but there were no algorithm triggered events. There were no n

• Cell adhesion to extracellular matrix requires the

  2019-05-17

  

  Cell adhesion to extracellular matrix requires the interaction of different molecules like selectins, cadherins and integrins [21]. Especially αvβ3 integrin has been proposed to mediate the adhesion of malignant cells in different entities such as multiple myeloma and breast cancer [22,23]. Upon exp

• mek inhibitors br Conclusion br Conflict of

  2019-05-17

  

  Conclusion Conflict of interest Introduction Giant cell tumor (GCT) is a primary intramedullary bone tumor that is composed of mononuclear and giant mononuclear cells, resembling mek inhibitors [1]. It usually involves the end of a long bone. The World Health Organization has classified GC

• br Es curioso observar que en

  2019-05-17

  

  Es curioso observar que en el terreno de la crítica musical, la tarea fundamental es evidentemente depurar la teoría de todo aquello que obstaculiza la formulación precisa de los elementos esenciales de la música. Sin embargo, cuando se trata de estudiar el tema de la música en la literatura, nada

• La reivindicaci n del m

  2019-05-17

  

  La reivindicación del mártir revolucionario El proceso del egp dio lugar Otamixaban consolidar un frente de estudiantes constituido con su línea política, trabajo continuo del estudiantado identificado con ello; respecto a la dirección de esta organización, carecemos de comunicados o publicaciones

• Bisphosphonates significantly reduce or prevent SREs

  2019-05-16

  

  Bisphosphonates significantly reduce or prevent SREs. The use of Zol for patients with bone metastases is currently the gold standard treatment [4]. However, it is still unclear whether Zol contributes to a survival benefit [9]. Niikura et al. recently reported that Zol did not prolong progression-f

• Seg n Alejandra Pita y Aimer

  2019-05-16

  

  Según Alejandra Pita y Aimer Granados, las revistas culturales han sido redescubiertas por los historiadores como fuente de enorme valor para el estudio de grupos y redes intelectuales, y en este aspecto se han constituido como objeto de estudio autónomo. Sin embargo, como hemos señalado anteriormen

• Declaration of interests br Abstract

  2019-05-16

  

  Declaration of interests Abstract Background In times of seawater inundation in coastal deltas, unprotected drinking water sources, such as ponds and shallow tube wells, take on salt water with each inundation. Daily consumption of these saline sources contributes to overall sodium intake. Altho

• Yang et al reported PSA

  2019-05-16

  

  Yang et al. reported PSA triggered TRUSP biopsy in Korea. This study included 75 patients younger than 40 years of age, with PSA > 4.0 ng/mL; the PCa detection rate was 1.3% in the Korean study. In comparison, there were substantially more abnormal DRE findings and significant LUTS findings in our s

• br Conflicts of interest br Funding

  2019-05-16

  

  Conflicts of interest Funding This study was supported by grants from the Ministry of Science and Technology, Taiwan (MOST-103-2314-B-002-090). Introduction Ancient schwannoma is an uncommon variant of schwannoma, which arises from the nerve sheath Schwann cells, with a typically long cour

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