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In human epidermoid carcinoma A
2024-11-11
In human epidermoid carcinoma A431 cells, 12-lipoxygenase was significantly increased in glutathione-depleted cells. The relative abundance of phospholipid hydroperoxide versus glutathione peroxidase seems to play an important role in controlling the lipoxygenase reaction [57]. It has been proposed
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ID-8 br AHR expression in cancer Perhaps the earliest indica
2024-11-11
AHR expression in cancer Perhaps the earliest indicator that the AHR might play an ongoing role in tumorigenesis, independent of its role in generating mutations, was the demonstration that non-genotoxic 2,3,7,8-tetrachlorodibenzo(p)dioxin (TCDD) is a carcinogen in animals and humans [7]. Althoug
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As regards feeding the ability to dissipate surplus energy i
2024-11-11
As regards feeding, the ability to dissipate surplus energy in the form of heat is beneficial for animals if the protein concentration in the food is low, since it allows them then to meet the adequate protein intake requirement without getting fat. Some of the major dietary activators of the AHR ar
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Introduction Glaucoma consists of a
2024-11-09
Introduction Glaucoma consists of a group of eye diseases showing a broad spectrum of clinical presentation and unknown aetiologies, that lead to a permanent loss of visual function due to the death of retinal ganglion sirtuin 1 and damage of the optical nerve. It is well accepted that a critical
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Cy5.5 hydrazide australia The Cebu Longitudinal Health and N
2024-11-09
The Cebu Longitudinal Health and Nutrition Survey (CLHNS) genome-wide association study investigated the genetic loci associated with plasma adiponectin in 1776 unrelated Filipino women. Adiponectin was strongly associated with three genetic positions: the gene CDH13 (rs3865188, P ≤ 7.2 × 10−16), ne
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Adenosine Kinase Inhibitor hydrate br Functional consequence
2024-11-09
Functional consequences of ADK regulation on astrocyte function As outlined above (see introduction), ADK critically regulates the extracellular adenosine levels in Adenosine Kinase Inhibitor hydrate (Boison, 2006, Etherington et al., 2009). Changes in the levels of adenosine, as a result of the
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Comparatively cell based assays appear
2024-11-09
Comparatively, cell-based assays appear to be the most sensitive method to detect patient autoantibodies directed at neurotransmitter receptors. Leite et al. demonstrated that many α-BTX RIA seronegative myasthenic patients do have autoantibodies against the AChR when a highly sensitive immunofluore
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The lanthanide series of chemical elements
2024-11-09
The lanthanide series of chemical elements comprises the fifteen metallic chemical elements with atomic numbers 57 through 71, from lanthanum to lutetium. Though originally described as ‘‘rare earths’’ because of their natural occurrence as metal oxides, they are not particularly rare. The lanthanid
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br Discussion One binding site
2024-11-09
Discussion One binding site, MB327-1 (Fig. 4) is located in the extracellular domain between the γ and α subunits. MB327 adopts an extended conformation in the MB327-1 site and is oriented parallel to the channel. The second putative binding site, MB327-2 (Fig. 4) is situated deep inside the chan
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The central problem in amnesia developing following
2024-11-09
The central problem in amnesia developing following impairment of long-term memory consolidation or reconsolidation is a question of the underlying mechanisms, whether it is caused by impairment of retrieval or memory storage mechanisms [3,8,9,[15], [16], [17], [18]]. To answer this question, severa
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Comparison of the GLUT positive
2024-11-09
Comparison of the GLUT1-positive plus ACLY negative group with the GLUT1-negative plus ACLY positive group indicated no significant difference with respect to disease-free survival and overall survival. However, some obvious differences in histological types were found in their formation. A previous
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Production of reactive oxygen species ROS during RSV infecti
2024-11-09
Production of reactive oxygen species (ROS) during RSV infection is one the important ways that neutrophils can injure the lungs [2], [24], [25]. Lipoxygenases are considered as an important source of producing ROS inside the Okadaic acid [26]. Several studies have indicated that the 12/15-LOX is a
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A positive correlation between nasopharyngeal CCL
2024-11-09
A positive correlation between nasopharyngeal CCL3 and CCL5 [16] concentrations and illness severity was shown in evaluating patients with RSV bronchiolitis [17]. CCL5 and CCL3 are important for monocyte and lymphocyte recruitment to the lung during RSV infection [7], [16], [18]. Despite the signifi
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In response to DSB the lesion recognition factor Mre Rad
2024-11-09
In response to DSB, the lesion recognition factor Mre11-Rad50-Nbs1 (MRN) complex helps the recruitment of ATM to the damage site and its activation by phosphorylation [29]. However, whether UV-damage recognition factors directly influence ATR and ATM recruitment and their phosphorylation is not clea
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br Mechanisms of homeostasis At
2024-11-09
Mechanisms of homeostasis At face value, homeostatic mechanisms may seem like nothing more than a simple balance between opposing forces; however, the ability of Mec1/Tel1 to each orchestrate both negative and positive regulation greatly complicates the system under consideration and argues again
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