• br Introduction Oral contraceptives OCs are the most

  2019-07-03

  

  Introduction Oral contraceptives (OCs) are the most commonly used medication for contraception all over the world and are also used in the treatment of menstrual disturbances and hyperandrogenism in women with polycystic ovary syndrome [1]. The impact of OC steroids on cardiovascular pathophysiol

• Prostaglandins PGs in particular PGE and PGF

  2019-07-03

  

  Prostaglandins (PGs), in particular PGE2 and PGF2α, play pivotal roles in human parturition by stimulating cervical ripening, myometrial contraction and fetal membrane rupture (Challis et al., 1997). In human pregnancy, the amnion is the principle source of PGE2 (Duchesne et al., 1978). In the amnio

• br Results and Discussion br Conclusions Understanding the

  2019-07-03

  

  Results and Discussion Conclusions Understanding the connections between function and fitness is a primary goal of many biological disciplines including systems biology and molecular evolution. While sound approaches have been developed to understand the connections between function and fitnes

• br Discussion Several DPP inhibitors are currently

  2019-07-03

  

  Discussion Several DPP-4 inhibitors are currently available for use in the treatment of type 2 diabetes mellitus. Due to the different chemical structures there are marked differences both in the binding kinetics on the target enzyme [10] and also different pathways of elimination [13] exist. In

• Possibly there are similarities among euphorb plant species

  2019-07-03

  

  Possibly there are similarities among euphorb plant species but extraction of the ldk378 structure present in the microsomal fraction is needed for testing their preferences for substrates. Although R. communis, E. lathyris and E. lagascae belong to the same family, the DGAT activity of their micros

• p is a tumor suppressor gene

  2019-07-03

  

  p16 is a tumor-suppressor gene that inhibits cyclin-dependent kinase 4 and 6 activities and arrests the dofetilide in the G1 phase. Aberrant methylation and mutation of p16/MTS1 in OSCC of patients was found in our previous study. Moreover, the frequency of hypermethylation of p16 from the present

• Previous and ongoing clinical trials have been

  2019-07-03

  

  Previous and ongoing clinical trials have been summarized in a recent review (Siaw-Debrah et al., 2017). To our knowledge, there are no ongoing or completed clinical trials focusing on cytokines in ICH. Published studies have focused mainly on cytokine changes in ICH patients (summarized in Table 3)

• Bafilomycin A1 br Materials and methods br Results The BUN

  2019-07-03

  

  Materials and methods Results The BUN and creatinine levels in the saline-treated CRF group were found to be significantly higher than those in the sham-operated control rats treated with either montelukast or saline (pand Bafilomycin A1 tissues, were found to be significantly higher in the s

• During the Lapita period in Tonga the Talasiu site would

  2019-07-03

  

  During the Lapita period in Tonga, the Talasiu site would have been an attractive location for human settlement as it overlooked an embayment holding large numbers of sessile and gregarious shellfish close to a fresh water solution channel, with gardening soils immediately inland. However, sea level

• System Analysis and Modeling In

  2019-07-03

  

  System Analysis and Modeling - In this work, a three-level hierarchical modeling – composed by combinatorial and state-space models – is used: (1) First, failure rates () of TMS servers subsystem units are estimated through continuous Markov chains; (2) Then, the single server Picroside II failure r

• The strong adsorption of amines to the

  2019-07-03

  

  The strong adsorption of amines to the stationary phase of gas chromatography (GC) columns causes issues such as tailing, ghosting and low reproducibility [12], [13]. A common practice to overcome this problem is the chemical derivatisation of amines prior to GC analysis [14]. Comprehensive reviews

• br DUBs in regulation of critical steps in tumor metastasis

  2019-07-02

  

  DUBs in regulation of critical steps in tumor metastasis Tumor metastasis comprises a complicated series of biological processes in terms of the invasion-metastasis cascade that requires cancer 5-Carboxymethylester-UTP weight to (1) migrate and invade from the origin sites through the extracellu

• The first hint that GLP might not be

  2019-07-02

  

  The first hint that GLP-1 might not be completely stable came from a meeting abstract in 1992, reporting that GLP-1 could be degraded in plasma incubations [16], although the enzyme(s) involved was not identified. A year later, Mentlein and colleagues [17], in a search for peptide substrates of the

• The in vivo IC M in the adipose tissue assay

  2019-07-02

  

  The in vivo IC (0.0003μM) in the adipose tissue assay is in very good agreement with the in vitro IC (0.0005μM), and it is larger than the one measured in the OLTT assay (0.00005μM) for this compound. These differences in in vivo IC between OLTT and TAG synthesis are expected as we used free CA-074

• Gene amplification PCR amplifications were

  2019-07-02

  

  Gene amplification. PCR amplifications were performed using genomic DNA from the different organisms studied as template and two degenerate oligonucleotides (PP1 and PP2) as primersPP1 corresponded to the sense codons of the amino hygromycin motif AGGI(A/S)EM, and PP2 to the antisense sequence of t

15931 records 997/1063 page Previous Next First page 上5页 9969979989991000 下5页 Last page