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Recently work has been focused on the adipose tissue derived
2018-11-08
Recently, work has been focused on the adipose tissue-derived stromal cell (ASCs) population, since retrieval is straight forward and non-harmful coupled to low-risk surgical procedures. However, biological properties of ASCs have only been assessed by indiscriminate isolation from mostly white fat
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Subsequent differentiation of stem cell derived MK
2018-11-08
Subsequent differentiation of stem cell-derived MK progenitors into mature MKs and ultimately platelets has been notoriously difficult. Coculture with OP9 or C3H10T1/2 stroma dopamine receptor antagonist has been found to greatly facilitate the process (Lu et al., 2011; Takayama et al., 2008), but
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br Results br Discussion In this
2018-11-08
Results Discussion In this study, we integrated transcriptome and proteome data and characterized the inventory of HSPCs and their immediate myeloid committed progeny (LS−K) (Figure S6). With almost 20,000 identified expressed genes including more than 3,000 significantly regulated ones, these
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Whereas most studies aiming at reprogramming brain resident
2018-11-08
Whereas most studies aiming at reprogramming brain-resident glia into neurons focused on astroglia, NG2 glia represent an interesting alternative cellular source given their abundance and life-long capacity for proliferation (Dimou and Götz, 2014). Here, we found that ∼60% of the induced DCX+ neuron
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Small molecules have demonstrated great
2018-11-08
Small molecules have demonstrated great potential in modulating cellular fate and functions. A milestone work showed that mouse iPSCs were successfully induced from mouse embryonic fibroblasts (MEF) via six chemical molecules, in the absence of Yamanaka reprogramming factors (Hou et al., 2013). Rec
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br Materials and methods br Results br Discussion
2018-11-08
Materials and methods Results Discussion During passaging, hESC undergo vigorous dynamic blebbing that prevents attachment and spreading of cells. If dynamic blebbing does not stop, raas inhibitor fail to attach, and eventually undergo apoptosis (Weng, 2016). Dynamic blebbing, which stress
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br Experimental Procedures br Acknowledgments We thank
2018-11-08
Experimental Procedures Acknowledgments We thank Drs. Robert Blelloch (UCSF) for the Dgcr8−/− ESCs, Jingyang Feng (Loyola Medical Center) for interpretation of histology results, Tim Townes (UAB) for comments on the manuscript, and the UAB Comprehensive Flow Cytometry Core (P30AR048311 and P30
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Multiple factors through binding to GPCRs
2018-11-08
Multiple factors, through binding to GPCRs, orchestrate the regulation of cAMP levels in a cell- and context-dependent manner, an effect that is most likely to be preserved during embryonic hematopoietic emergence and development (Diaz et al., 2015; Goessling et al., 2011; Hoggatt et al., 2009; Jing
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We previously identified a minimal surface phenotype suited
2018-11-08
We previously identified a minimal surface phenotype suited not only to enrich the archetypal human “MSCs” in uncultured BM cell suspensions, but also to correlate their ex vivo-assayed clonogenic capacity with their in situ identity and in vivo fate following transplantation (Sacchetti et al., 2007
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The paper is organized as follows After
2018-11-07
The paper is organized as follows. After describing our data sources and methods, we examine variation in probability of survival to age 70 (S70) across US counties, extending previous research (Cullen, Cummins, & Fuchs, 2012) and showing that women consistently exhibit greater survival “resilience”
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In conclusion extending results of prior analyses Grossman
2018-11-07
In conclusion, extending results of prior analyses (Grossman & Jacobwitz, 1981; Corman & Grossman, 1985; Joyce, 1987a, 1987b; Meier & McFarlane, 1994; McFarlane & Meier, 1998, 2001), our study provides contemporary evidence that state-only expenditures for reproductive services S63845 for infant de
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The average schooling of the
2018-11-07
The average schooling of the two groups is noteworthy; individuals with health problems have on average 5.6 years of schooling, while individuals without health problems have a much higher average schooling, 8.3 years. This result has been found in several studies. The relationship between health an
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At months of age no obvious physical abnormalities were foun
2018-11-07
At 51 months of age, no obvious physical abnormalities were found. Kampo (yokukansan) showed no effect but clonazepam (0.1–0.2mg) showed favorable effects on the intensity and frequency of arm banging. We have attempted to increase the dose of clonazepam gradually, but no complete remission has been
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muscarinic receptor antagonists Un estudio realizado por Han
2018-11-07
Un estudio realizado por Hanson (2010) revisó las posibles explicaciones de porqué México no ha tenido tasas de crecimiento económico altas, y compara el desempeño con el de otros países de América Latina (Argentina, Brasil, Chile y Venezuela) entre 1985 y 2008. El análisis de Hanson muestra que Méx
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El pobre desempe o de la inversi n y la
2018-11-07
El pobre desempeño de la inversión y la dependencia de la importación de capital fijo se dan pari passu con una aletargada evolución del producto nacional. Al respecto, Ros (2008) con antelación señala que ello se explica por la baja tasa de acumulación de capital físico. Cabe recordar que el énfasi
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